University of Zagreb
Faculty of Science
Graduate studies in Biology/Toxicology
Lecturers: Jasna Kniewald i Elsa Reiner
Molecular and cellular aspects of toxicity . Mechanism of transport of xenobiotics through cell membranes. Binding to proteins. Biotransformation of toxic compounds. Binding to receptors. Factors influencing metabolism, deposition and excretion of xenobiotics. Specific examples: toxicity of metals, organophosphorus compounds, pesticides, organic solvents and effect of radiation.
J.A. Timbrell: Principles of Biochemical Toxicology, Taylor & Francis Ltd., London (1992)
L.C. Lu: Basic Toxicology: Fundamentals, Target Organs and Risk Assesment, 2nd edition, Hemisphere Publishing Corporation, Washington (1991)
E. Giacobini (editor): Cholinesterases and Cholinesterase Inhibitors, Martin Dunitz Ltd., London (2000)